KMID : 0882420130850050503
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Korean Journal of Medicine 2013 Volume.85 No. 5 p.503 ~ p.506
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A Case of Drug-Induced Autoimmune Hepatitis after Glucosamine Ingestion
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Kwon Seong-Soon
Wee Jee-Wan Park Jung-Wan Yoon Seug-Yun Jeong Soung-Won Jang Jae-Young Jin Yoon-Mi
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Abstract
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Herbal remedies and health foods are widely used, and their side effects have been reported. Glucosamine is a naturally occurring amino-monosaccharide and a safe health food; rarely, however, it can cause cholestatic and hepatocellular hepatitis. We describe a case of drug-induced autoimmune hepatitis after ingestion of glucosamine. A middle-aged woman who had no history of liver disease complained of jaundice after taking glucosamine. The diagnosis of drug-induced acute autoimmune hepatitis was made using the Roussel Uclaf Causality Assessment Method score based on the patient¡¯s history and laboratory data, and percutaneous liver biopsy. After supportive care and administering prednisolone and azathiprine, the patient showed rapid improvement in clinical symptoms and laboratory findings.
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KEYWORD
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Glucosamine, Toxic hepatitis, Autoimmune hepatitis, Drug induced autoimmune hepatitis
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